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DrugDisc
A novel strategy for treating immune-suppressive breast cancer: pharmacological prevention of CD73 deubiquitination (Zhu et al., J Clinical Investigation 2024)
Allosteric modulation of parathyroid hormone receptor (PTHR) for regulating calcium signaling and endocrine homeostasis (Sutkeviciute et al Nature Chem Biol, 2022)
Recognition of SARS-CoV-2 spike superantigenic segment by T cell receptors (Cheng et al., PNAS 2020)
Targeting Cyt c peroxidase activity by imidazole substituted fatty acids for treating Barth syndrome (Kagan et al., Nature Metabolism, 2024)
Development of new methodology for pharmacophore modeling: Pharmmaker (Lee et al. Protein Sci 2020)
Design of small molecule activators of protein phosphatase (PP2A) - a tumor suppressor protein

Targeting of allosteric sites as a strategy for complementing orthosteric site targeting and alleviating drug resistance
Design, synthesis and characterization of positive allosteric modulators (PAMs) of excitatory amino acid transporter 2 (EAAT2) (Fontana et al. J Med Chem, 2024)