NetBio

Cover page of a presentation titled 'Elastic Network Model' with a background of colorful protein structures.

Network models are everywhere:

from intramolecular, to cellular networks, gene networks, to the connectome

A detailed molecular model of a virus, showing its complex protein structure with various colored atoms representing different elements.
Diagram showing elastic network models with a protein structure, a network of beads and springs, and a magnified view of springs connecting residues within a cutoff distance.
Diagram explaining chromatin dynamics and genetic interaction networks; includes heatmaps, a color-coded genome map, and network graphs with nodes and edges representing gene interactions.

Bahar lab introduced the elastic network models (ENMs) for protein dynamics. ENMs have been extended to exploring chromosomal dynamics, gene-regulatory networks, and the brain connectome.

Labs of Lilianne Mujica-Parodi, Ken A. Dill and Steven Skiena are coming together to further investigate…

What are the “rules” by which the brain self-organizes in response to resource constraints?

Does neuronal metabolism “bend” before it “breaks”?

If so, is there a critical window during which intervention can most effectively prevent age-based cognitive decline?

Learn more about Dr. Mujica-Parodi and LCNeuro here