LC Seminar- Stephanie Weber
Stephanie Weber, Associate Professor at McGill University
10/17 in LC 101 @12:30 PM
Talk Title: “Multiphase behavior of the nucleolus throughout the C. elegans life cycle”
Abstract: Cells contain a variety of membraneless compartments that assemble through phase separation. Some of these biomolecular condensates, such as stress granules, form transiently, while others, like the nucleolus, are constitutive. However, even constitutive condensates are sensitive to developmental and environmental conditions. Here, we use quantitative live-cell imaging to characterize the morphology and subcompartmentalization of the nucleolus throughout the C. elegans life cycle. Our results suggest that organisms can tune the physical properties of biomolecular condensates, and perhaps their function, in response to internal and external cues.
